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Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes
Fibroblastic reticular cells (FRC) form the structural backbone of the T cell rich zones in secondary lymphoid organs (SLO), but also actively influence the adaptive immune response. They provide a guidance path for immigrating T lymphocytes and dendritic cells (DC) and are the main local source of...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438460/ https://www.ncbi.nlm.nih.gov/pubmed/22973278 http://dx.doi.org/10.3389/fimmu.2012.00285 |