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Regulation of VEGF expression by HIF-1α in the femoral head cartilage following ischemia osteonecrosis

Juvenile femoral head osteonecrosis is due to disruption of blood supply which results in ischemic injury. Angiogenesis is an essential component for the healing of damaged head. Hypoxia-inducible factor-1α (HIF-1α) is a master regulator of cellular response to hypoxia. Our histological studies show...

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Detalles Bibliográficos
Autores principales: Zhang, Chi, Li, Yang, Cornelia, Reuel, Swisher, Susanne, Kim, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438463/
https://www.ncbi.nlm.nih.gov/pubmed/22970342
http://dx.doi.org/10.1038/srep00650