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β-hairpin forms by rolling up from C-terminal: Topological guidance of early folding dynamics
That protein folding is a non-random, guided process has been known even prior to Levinthal's paradox; yet, guided searches, attendant mechanisms and their relation to primary sequence remain obscure. Using extensive molecular dynamics simulations of a β-hairpin with key sequence features simil...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438464/ https://www.ncbi.nlm.nih.gov/pubmed/22970341 http://dx.doi.org/10.1038/srep00649 |