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Induction of Th17 cell differentiation by B-1 cells

B-1 cells constitute a unique B cell population with distinct ontogenic, phenotypic, and functional characteristics. Naïve, unmanipulated B-1 cells induce differentiation of CD4(+) T cells to become pro-inflammatory Th17 cells whereas naïve B-2 cells do not. We examined the role of distinctly expres...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Rothstein, Thomas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438481/
https://www.ncbi.nlm.nih.gov/pubmed/22973276
http://dx.doi.org/10.3389/fimmu.2012.00281