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PIDDosome-independent tumor suppression by Caspase-2

The PIDDosome, a multiprotein complex constituted of the ‘p53-induced protein with a death domain (PIDD), ‘receptor-interacting protein (RIP)-associated ICH-1/CED-3 homologous protein with a death domain' (RAIDD) and pro-Caspase-2 has been defined as an activating platform for this apoptosis-re...

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Detalles Bibliográficos
Autores principales: Manzl, C, Peintner, L, Krumschnabel, G, Bock, F, Labi, V, Drach, M, Newbold, A, Johnstone, R, Villunger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438502/
https://www.ncbi.nlm.nih.gov/pubmed/22595758
http://dx.doi.org/10.1038/cdd.2012.54