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The role of PML ubiquitination in human malignancies

Tumor suppressors are frequently downregulated in human cancers and understanding of the mechanisms through which tumor cells restrict the expression of tumor suppressors is important for the prognosis and intervention of diseases. The promyelocytic leukemia (PML) protein plays a critical role in mu...

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Detalles Bibliográficos
Autores principales: Chen, Ruey-Hwa, Lee, Yu-Ru, Yuan, Wei-Chien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438505/
https://www.ncbi.nlm.nih.gov/pubmed/22935031
http://dx.doi.org/10.1186/1423-0127-19-81