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Bayesian Methods for Multivariate Modeling of Pleiotropic SNP Associations and Genetic Risk Prediction

Genome-wide association studies (GWAS) have identified numerous associations between genetic loci and individual phenotypes; however, relatively few GWAS have attempted to detect pleiotropic associations, in which loci are simultaneously associated with multiple distinct phenotypes. We show that ple...

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Detalles Bibliográficos
Autores principales: Hartley, Stephen W., Monti, Stefano, Liu, Ching-Ti, Steinberg, Martin H., Sebastiani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438684/
https://www.ncbi.nlm.nih.gov/pubmed/22973300
http://dx.doi.org/10.3389/fgene.2012.00176