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Bayesian Methods for Multivariate Modeling of Pleiotropic SNP Associations and Genetic Risk Prediction
Genome-wide association studies (GWAS) have identified numerous associations between genetic loci and individual phenotypes; however, relatively few GWAS have attempted to detect pleiotropic associations, in which loci are simultaneously associated with multiple distinct phenotypes. We show that ple...
Autores principales: | Hartley, Stephen W., Monti, Stefano, Liu, Ching-Ti, Steinberg, Martin H., Sebastiani, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438684/ https://www.ncbi.nlm.nih.gov/pubmed/22973300 http://dx.doi.org/10.3389/fgene.2012.00176 |
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