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The MET Oncogene as a Therapeutical Target in Cancer Invasive Growth

The MET proto-oncogene, encoding the tyrosine kinase receptor for Hepatocyte Growth Factor (HGF) regulates invasive growth, a genetic program that associates control of cell proliferation with invasion of the extracellular matrix and protection from apoptosis. Physiologically, invasive growth takes...

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Detalles Bibliográficos
Autores principales: Luraghi, Paolo, Schelter, Florian, Krüger, Achim, Boccaccio, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438853/
https://www.ncbi.nlm.nih.gov/pubmed/22973229
http://dx.doi.org/10.3389/fphar.2012.00164