Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling

Polyubiquitin (polyUb) chain topology is thought to direct modified substrates to specific fates, but this function-topology relationship is poorly understood, as are the dynamics and subcellular locations of specific polyUb signals. Experimental access to these questions has been limited because li...

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Detalles Bibliográficos
Autores principales: Sims, Joshua J., Scavone, Francesco, Cooper, Eric M., Kane, Lesley A., Youle, Richard J., Boeke, Jef D., Cohen, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438894/
https://www.ncbi.nlm.nih.gov/pubmed/22306808
http://dx.doi.org/10.1038/nmeth.1888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438894/
https://www.ncbi.nlm.nih.gov/pubmed/22306808
http://dx.doi.org/10.1038/nmeth.1888

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