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Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling
Polyubiquitin (polyUb) chain topology is thought to direct modified substrates to specific fates, but this function-topology relationship is poorly understood, as are the dynamics and subcellular locations of specific polyUb signals. Experimental access to these questions has been limited because li...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438894/ https://www.ncbi.nlm.nih.gov/pubmed/22306808 http://dx.doi.org/10.1038/nmeth.1888 |