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Genome-wide Epigenetic Data Facilitate Understanding of Disease Susceptibility Association Studies
Complex traits such as susceptibility to diseases are determined in part by variants at multiple genetic loci. Genome-wide association studies can identify these loci, but most phenotype-associated variants lie distal to protein-coding regions and are likely involved in regulating gene expression. U...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American Society for Biochemistry and Molecular Biology
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438926/ https://www.ncbi.nlm.nih.gov/pubmed/22952232 http://dx.doi.org/10.1074/jbc.R112.352427 |