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Increased NMDA receptor inhibition at an increased Sevoflurane MAC

BACKGROUND: Sevoflurane potently enhances glycine receptor currents and more modestly decreases NMDA receptor currents, each of which may contribute to immobility. This modest NMDA receptor antagonism by sevoflurane at a minimum alveolar concentration (MAC) could be reciprocally related to large pot...

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Detalles Bibliográficos
Autores principales: Brosnan, Robert J, Thiesen, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439310/
https://www.ncbi.nlm.nih.gov/pubmed/22672766
http://dx.doi.org/10.1186/1471-2253-12-9