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Genomic characterization of explant tumorgraft models derived from fresh patient tumor tissue
BACKGROUND: There is resurgence within drug and biomarker development communities for the use of primary tumorgraft models as improved predictors of patient tumor response to novel therapeutic strategies. Despite perceived advantages over cell line derived xenograft models, there is limited data com...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439334/ https://www.ncbi.nlm.nih.gov/pubmed/22709571 http://dx.doi.org/10.1186/1479-5876-10-125 |