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Long-term impact of systemic bacterial infection on the cerebral vasculature and microglia

BACKGROUND: Systemic infection leads to generation of inflammatory mediators that result in metabolic and behavioural changes. Repeated or chronic systemic inflammation leads to a state of innate immune tolerance: a protective mechanism against overactivity of the immune system. In this study, we in...

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Detalles Bibliográficos
Autores principales: Püntener, Ursula, Booth, Steven G, Perry, V Hugh, Teeling, Jessica L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439352/
https://www.ncbi.nlm.nih.gov/pubmed/22738332
http://dx.doi.org/10.1186/1742-2094-9-146