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Long-term impact of systemic bacterial infection on the cerebral vasculature and microglia
BACKGROUND: Systemic infection leads to generation of inflammatory mediators that result in metabolic and behavioural changes. Repeated or chronic systemic inflammation leads to a state of innate immune tolerance: a protective mechanism against overactivity of the immune system. In this study, we in...
Autores principales: | Püntener, Ursula, Booth, Steven G, Perry, V Hugh, Teeling, Jessica L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439352/ https://www.ncbi.nlm.nih.gov/pubmed/22738332 http://dx.doi.org/10.1186/1742-2094-9-146 |
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