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Norcantharidin Facilitates LPS-Mediated Immune Responses by Up-Regulation of AKT/NF-κB Signaling in Macrophages

Norcantharidin (NCTD), a demethylated analog of cantharidin, is a common used clinical drug to inhibit proliferation and metastasis of cancer cells. But the role of NCTD in modulating immune responses remains unknown. Here, we investigated the function and mechanism of NCTD in regulation of TLR4 ass...

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Detalles Bibliográficos
Autores principales: Zhao, Qufei, Qian, Yu, Li, Ruimei, Tan, Binghe, Han, Honghui, Liu, Mingyao, Qian, Min, Du, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439369/
https://www.ncbi.nlm.nih.gov/pubmed/22984593
http://dx.doi.org/10.1371/journal.pone.0044956