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Deficiency of the Promyelocytic Leukemia Protein Fosters Hepatitis C-Associated Hepatocarcinogenesis in Mice

Overwhelming lines of epidemiological evidence have indicated that persistent infection with hepatitis C virus (HCV) is a major risk for the development of hepatocellular carcinoma (HCC). We have recently shown that HCV core protein mediates functional inactivation of the promyelocytic leukemia (PML...

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Detalles Bibliográficos
Autores principales: Herzer, Kerstin, Carbow, Anna, Sydor, Svenja, Sowa, Jan-Peter, Biesterfeld, Stefan, Hofmann, Thomas-Georg, Galle, Peter-Robert, Gerken, Guido, Canbay, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439406/
https://www.ncbi.nlm.nih.gov/pubmed/22984515
http://dx.doi.org/10.1371/journal.pone.0044474