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Deficiency of the Promyelocytic Leukemia Protein Fosters Hepatitis C-Associated Hepatocarcinogenesis in Mice
Overwhelming lines of epidemiological evidence have indicated that persistent infection with hepatitis C virus (HCV) is a major risk for the development of hepatocellular carcinoma (HCC). We have recently shown that HCV core protein mediates functional inactivation of the promyelocytic leukemia (PML...
Autores principales: | Herzer, Kerstin, Carbow, Anna, Sydor, Svenja, Sowa, Jan-Peter, Biesterfeld, Stefan, Hofmann, Thomas-Georg, Galle, Peter-Robert, Gerken, Guido, Canbay, Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439406/ https://www.ncbi.nlm.nih.gov/pubmed/22984515 http://dx.doi.org/10.1371/journal.pone.0044474 |
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