Multi-Scale Biomechanical Remodeling in Aging and Genetic Mutant Murine Mitral Valve Leaflets: Insights into Marfan Syndrome

Mitral valve degeneration is a key component of the pathophysiology of Marfan syndrome. The biomechanical consequences of aging and genetic mutation in mitral valves are poorly understood because of limited tools to study this in mouse models. Our aim was to determine the global biomechanical and lo...

Descripción completa

Detalles Bibliográficos
Autores principales: Gould, Russell A., Sinha, Ravi, Aziz, Hamza, Rouf, Rosanne, Dietz, Harry C., Judge, Daniel P., Butcher, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439411/
https://www.ncbi.nlm.nih.gov/pubmed/22984535
http://dx.doi.org/10.1371/journal.pone.0044639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439411/
https://www.ncbi.nlm.nih.gov/pubmed/22984535
http://dx.doi.org/10.1371/journal.pone.0044639

Ejemplares similares