Unlike Pancreatic Cancer Cells Pancreatic Cancer Associated Fibroblasts Display Minimal Gene Induction after 5-Aza-2′-Deoxycytidine

PURPOSE: Cancer associated stromal fibroblasts (CAFs) undergo transcriptional and phenotypic changes that contribute to tumor progression, but the mechanisms responsible for these changes are not well understood. Aberrant DNA methylation is an important cause of transcriptional alterations in cancer...

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Detalles Bibliográficos
Autores principales: Yu, Jun, Walter, Kimberly, Omura, Noriyuki, Hong, Seung-Mo, Young, Angela, Li, Ang, Vincent, Audrey, Goggins, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439436/
https://www.ncbi.nlm.nih.gov/pubmed/22984426
http://dx.doi.org/10.1371/journal.pone.0043456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439436/
https://www.ncbi.nlm.nih.gov/pubmed/22984426
http://dx.doi.org/10.1371/journal.pone.0043456

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