Sub-Domains of Ricin’s B Subunit as Targets of Toxin Neutralizing and Non-Neutralizing Monoclonal Antibodies

The B subunit (RTB) of ricin toxin is a galactose (Gal)−/N-acetylgalactosamine (GalNac)-specific lectin that mediates attachment, entry, and intracellular trafficking of ricin in host cells. Structurally, RTB consists of two globular domains with identical folding topologies. Domains 1 and 2 are eac...

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Detalles Bibliográficos
Autores principales: Yermakova, Anastasiya, Vance, David J., Mantis, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439471/
https://www.ncbi.nlm.nih.gov/pubmed/22984492
http://dx.doi.org/10.1371/journal.pone.0044317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439471/
https://www.ncbi.nlm.nih.gov/pubmed/22984492
http://dx.doi.org/10.1371/journal.pone.0044317

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