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Phosphatidylcholine formation by LPCAT1 is regulated by Ca(2+) and the redox status of the cell

BACKGROUND: Unsaturated fatty acids are susceptible to oxidation and damaged chains are removed from glycerophospholipids by phospholipase A(2). De-acylated lipids are then re-acylated by lysophospholipid acyltransferase enzymes such as LPCAT1 which catalyses the formation of phosphatidylcholine (PC...

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Detalles Bibliográficos
Autores principales: Soupene, Eric, Kuypers, Frans A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439698/
https://www.ncbi.nlm.nih.gov/pubmed/22676268
http://dx.doi.org/10.1186/1471-2091-13-8