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Phosphatidylcholine formation by LPCAT1 is regulated by Ca(2+) and the redox status of the cell
BACKGROUND: Unsaturated fatty acids are susceptible to oxidation and damaged chains are removed from glycerophospholipids by phospholipase A(2). De-acylated lipids are then re-acylated by lysophospholipid acyltransferase enzymes such as LPCAT1 which catalyses the formation of phosphatidylcholine (PC...
Autores principales: | Soupene, Eric, Kuypers, Frans A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439698/ https://www.ncbi.nlm.nih.gov/pubmed/22676268 http://dx.doi.org/10.1186/1471-2091-13-8 |
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