Orf virus interferes with MHC class I surface expression by targeting vesicular transport and Golgi

BACKGROUND: The Orf virus (ORFV), a zoonotic Parapoxvirus, causes pustular skin lesions in small ruminants (goat and sheep). Intriguingly, ORFV can repeatedly infect its host, despite the induction of a specific immunity. These immune modulating and immune evading properties are still unexplained. R...

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Detalles Bibliográficos
Autores principales: Emschermann, Frederic, Knittler, Michael R, Rziha, Hanns-Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439706/
https://www.ncbi.nlm.nih.gov/pubmed/22809544
http://dx.doi.org/10.1186/1746-6148-8-114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439706/
https://www.ncbi.nlm.nih.gov/pubmed/22809544
http://dx.doi.org/10.1186/1746-6148-8-114

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