Investigating drug repositioning opportunities in FDA drug labels through topic modeling

BACKGROUND: Drug repositioning offers an opportunity to revitalize the slowing drug discovery pipeline by finding new uses for currently existing drugs. Our hypothesis is that drugs sharing similar side effect profiles are likely to be effective for the same disease, and thus repositioning opportuni...

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Detalles Bibliográficos
Autores principales: Bisgin, Halil, Liu, Zhichao, Kelly, Reagan, Fang, Hong, Xu, Xiaowei, Tong, Weida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439728/
https://www.ncbi.nlm.nih.gov/pubmed/23046522
http://dx.doi.org/10.1186/1471-2105-13-S15-S6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439728/
https://www.ncbi.nlm.nih.gov/pubmed/23046522
http://dx.doi.org/10.1186/1471-2105-13-S15-S6

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