Using a priori knowledge to align sequencing reads to their exact genomic position

The use of a priori knowledge in the alignment of targeted sequencing data is investigated using computational experiments. Adapting a Needleman–Wunsch algorithm to incorporate the genomic position information from the targeted capture, we demonstrate that alignment can be done to just the target re...

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Detalles Bibliográficos
Autores principales: Böttcher, René, Amberg, Ronny, Ruzius, F. P., Guryev, V., Verhaegh, Wim F. J., Beyerlein, Peter, van der Zaag, P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439880/
https://www.ncbi.nlm.nih.gov/pubmed/22581774
http://dx.doi.org/10.1093/nar/gks393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439880/
https://www.ncbi.nlm.nih.gov/pubmed/22581774
http://dx.doi.org/10.1093/nar/gks393

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