Targeting duplex DNA with chimeric α,β-triplex-forming oligonucleotides

Triplex-directed DNA recognition is strictly limited by polypurine sequences. In an attempt to address this problem with synthetic biology tools, we designed a panel of short chimeric α,β-triplex-forming oligonucleotides (TFOs) and studied their interaction with fluorescently labelled duplex hairpin...

Descripción completa

Detalles Bibliográficos
Autores principales: Kolganova, N. A., Shchyolkina, A. K., Chudinov, A. V., Zasedatelev, A. S., Florentiev, V. L., Timofeev, E. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439883/
https://www.ncbi.nlm.nih.gov/pubmed/22641847
http://dx.doi.org/10.1093/nar/gks410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439883/
https://www.ncbi.nlm.nih.gov/pubmed/22641847
http://dx.doi.org/10.1093/nar/gks410

Ejemplares similares