A new strategy to reduce allelic bias in RNA-Seq readmapping

Accurate estimation of expression levels from RNA-Seq data entails precise mapping of the sequence reads to a reference genome. Because the standard reference genome contains only one allele at any given locus, reads overlapping polymorphic loci that carry a non-reference allele are at least one mis...

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Detalles Bibliográficos
Autores principales: Vijaya Satya, Ravi, Zavaljevski, Nela, Reifman, Jaques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439884/
https://www.ncbi.nlm.nih.gov/pubmed/22584625
http://dx.doi.org/10.1093/nar/gks425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439884/
https://www.ncbi.nlm.nih.gov/pubmed/22584625
http://dx.doi.org/10.1093/nar/gks425

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