Cargando…
A new strategy to reduce allelic bias in RNA-Seq readmapping
Accurate estimation of expression levels from RNA-Seq data entails precise mapping of the sequence reads to a reference genome. Because the standard reference genome contains only one allele at any given locus, reads overlapping polymorphic loci that carry a non-reference allele are at least one mis...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439884/ https://www.ncbi.nlm.nih.gov/pubmed/22584625 http://dx.doi.org/10.1093/nar/gks425 |