Hydrogen bond formation between the naturally modified nucleobase and phosphate backbone

Natural RNAs, especially tRNAs, are extensively modified to tailor structure and function diversities. Uracil is the most modified nucleobase among all natural nucleobases. Interestingly, >76% of uracil modifications are located on its 5-position. We have investigated the natural 5-methoxy (5-O-C...

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Detalles Bibliográficos
Autores principales: Sheng, Jia, Zhang, Wen, Hassan, Abdalla E. A., Gan, Jianhua, Soares, Alexei S., Geng, Song, Ren, Yi, Huang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439885/
https://www.ncbi.nlm.nih.gov/pubmed/22641848
http://dx.doi.org/10.1093/nar/gks426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439885/
https://www.ncbi.nlm.nih.gov/pubmed/22641848
http://dx.doi.org/10.1093/nar/gks426

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