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Heterochromatin protein 1 gamma and IκB kinase alpha interdependence during tumour necrosis factor gene transcription elongation in activated macrophages
IκB kinase α (IKKα) is part of the cytoplasmic IKK complex regulating nuclear factor-{kappa}B (NF-κB) release and translocation into the nucleus in response to pro-inflammatory signals. IKKα can also be recruited directly to the promoter of NF-κB-dependent genes by NF-κB where it phosphorylates hist...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439902/ https://www.ncbi.nlm.nih.gov/pubmed/22649058 http://dx.doi.org/10.1093/nar/gks509 |