Heterochromatin protein 1 gamma and IκB kinase alpha interdependence during tumour necrosis factor gene transcription elongation in activated macrophages

IκB kinase α (IKKα) is part of the cytoplasmic IKK complex regulating nuclear factor-{kappa}B (NF-κB) release and translocation into the nucleus in response to pro-inflammatory signals. IKKα can also be recruited directly to the promoter of NF-κB-dependent genes by NF-κB where it phosphorylates hist...

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Detalles Bibliográficos
Autores principales: Thorne, James L., Ouboussad, Lylia, Lefevre, Pascal F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439902/
https://www.ncbi.nlm.nih.gov/pubmed/22649058
http://dx.doi.org/10.1093/nar/gks509

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