Structural flexibility of RNA as molecular basis for Hfq chaperone function

In enteric bacteria, many small regulatory RNAs (sRNAs) associate with the RNA chaperone host factor Q (Hfq) and often require the protein for regulation of target mRNAs. Previous studies suggested that the hexameric Escherichia coli Hfq (Hfq(Ec)) binds sRNAs on the proximal site, whereas the distal...

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Detalles Bibliográficos
Autores principales: de Almeida Ribeiro, Euripedes, Beich-Frandsen, Mads, Konarev, Petr V., Shang, Weifeng, Večerek, Branislav, Kontaxis, Georg, Hämmerle, Hermann, Peterlik, Herwig, Svergun, Dmitri I., Bläsi, Udo, Djinović-Carugo, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439903/
https://www.ncbi.nlm.nih.gov/pubmed/22718981
http://dx.doi.org/10.1093/nar/gks510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439903/
https://www.ncbi.nlm.nih.gov/pubmed/22718981
http://dx.doi.org/10.1093/nar/gks510

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