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eIF4E-binding protein regulation of mRNAs with differential 5′-UTR secondary structure: a polyelectrostatic model for a component of protein–mRNA interactions

Control of translation in eukaryotes is complex, depending on the binding of various factors to mRNAs. Available data for subsets of mRNAs that are translationally up- and down-regulated in yeast eIF4E-binding protein (4E-BP) deletion mutants are coupled with reported mRNA secondary structure measur...

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Detalles Bibliográficos
Autores principales: Cawley, Andrew, Warwicker, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439904/
https://www.ncbi.nlm.nih.gov/pubmed/22718971
http://dx.doi.org/10.1093/nar/gks511