Single-molecule microscopy reveals new insights into nucleotide selection by DNA polymerase I

The mechanism by which DNA polymerases achieve their extraordinary accuracy has been intensely studied because of the linkage between this process and mutagenesis and carcinogenesis. Here, we have used single-molecule fluorescence microscopy to study the process of nucleotide selection and exonuclea...

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Detalles Bibliográficos
Autores principales: Markiewicz, Radoslaw P., Vrtis, Kyle B., Rueda, David, Romano, Louis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439913/
https://www.ncbi.nlm.nih.gov/pubmed/22669904
http://dx.doi.org/10.1093/nar/gks523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439913/
https://www.ncbi.nlm.nih.gov/pubmed/22669904
http://dx.doi.org/10.1093/nar/gks523

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