Cargando…

Cross talk between the nuclease and helicase activities of Dna2: role of an essential iron–sulfur cluster domain

Dna2 nuclease/helicase is a multitasking protein involved in DNA replication and recombinational repair, and it is important for preservation of genomic stability. Yeast Dna2 protein contains a conserved putative Fe–S (iron–sulfur) cluster signature motif spanning the nuclease active site. We show t...

Descripción completa

Detalles Bibliográficos
Autores principales: Pokharel, Subhash, Campbell, Judith L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439918/
https://www.ncbi.nlm.nih.gov/pubmed/22684504
http://dx.doi.org/10.1093/nar/gks534