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Cross talk between the nuclease and helicase activities of Dna2: role of an essential iron–sulfur cluster domain
Dna2 nuclease/helicase is a multitasking protein involved in DNA replication and recombinational repair, and it is important for preservation of genomic stability. Yeast Dna2 protein contains a conserved putative Fe–S (iron–sulfur) cluster signature motif spanning the nuclease active site. We show t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439918/ https://www.ncbi.nlm.nih.gov/pubmed/22684504 http://dx.doi.org/10.1093/nar/gks534 |