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CTCF-mediated transcriptional regulation through cell type-specific chromosome organization in the β-globin locus

The principles underlying the architectural landscape of chromatin beyond the nucleosome level in living cells remains largely unknown despite its potential to play a role in mammalian gene regulation. We investigated the three-dimensional folding of a 1 Mbp region of human chromosome 11 containing...

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Detalles Bibliográficos
Autores principales: Junier, Ivan, Dale, Ryan K., Hou, Chunhui, Képès, François, Dean, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439919/
https://www.ncbi.nlm.nih.gov/pubmed/22705794
http://dx.doi.org/10.1093/nar/gks536