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CTCF-mediated transcriptional regulation through cell type-specific chromosome organization in the β-globin locus
The principles underlying the architectural landscape of chromatin beyond the nucleosome level in living cells remains largely unknown despite its potential to play a role in mammalian gene regulation. We investigated the three-dimensional folding of a 1 Mbp region of human chromosome 11 containing...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439919/ https://www.ncbi.nlm.nih.gov/pubmed/22705794 http://dx.doi.org/10.1093/nar/gks536 |