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Genome-wide localization and expression profiling establish Sp2 as a sequence-specific transcription factor regulating vitally important genes
The transcription factor Sp2 is essential for early mouse development and for proliferation of mouse embryonic fibroblasts in culture. Yet its mechanisms of action and its target genes are largely unknown. In this study, we have combined RNA interference, in vitro DNA binding, chromatin immunoprecip...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439921/ https://www.ncbi.nlm.nih.gov/pubmed/22684502 http://dx.doi.org/10.1093/nar/gks544 |