How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T–product complexes

Exonucleases are key enzymes in the maintenance of genome stability, processing of immature RNA precursors and degradation of unnecessary nucleic acids. However, it remains unclear how exonucleases digest nucleic acids to generate correct end products for next-step processing. Here we show how the e...

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Detalles Bibliográficos
Autores principales: Hsiao, Yu-Yuan, Duh, Yulander, Chen, Yi-Ping, Wang, Yi-Ting, Yuan, Hanna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439924/
https://www.ncbi.nlm.nih.gov/pubmed/22718982
http://dx.doi.org/10.1093/nar/gks548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439924/
https://www.ncbi.nlm.nih.gov/pubmed/22718982
http://dx.doi.org/10.1093/nar/gks548

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