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How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T–product complexes
Exonucleases are key enzymes in the maintenance of genome stability, processing of immature RNA precursors and degradation of unnecessary nucleic acids. However, it remains unclear how exonucleases digest nucleic acids to generate correct end products for next-step processing. Here we show how the e...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439924/ https://www.ncbi.nlm.nih.gov/pubmed/22718982 http://dx.doi.org/10.1093/nar/gks548 |