An integrative probabilistic model for identification of structural variation in sequencing data

Paired-end sequencing is a common approach for identifying structural variation (SV) in genomes. Discrepancies between the observed and expected alignments indicate potential SVs. Most SV detection algorithms use only one of the possible signals and ignore reads with multiple alignments. This result...

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Detalles Bibliográficos
Autores principales: Sindi, Suzanne S, Önal, Selim, Peng, Luke C, Wu, Hsin-Ta, Raphael, Benjamin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439973/
https://www.ncbi.nlm.nih.gov/pubmed/22452995
http://dx.doi.org/10.1186/gb-2012-13-3-r22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439973/
https://www.ncbi.nlm.nih.gov/pubmed/22452995
http://dx.doi.org/10.1186/gb-2012-13-3-r22

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