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Bag3-Induced Autophagy Is Associated with Degradation of JCV Oncoprotein, T-Ag

JC virus, JCV, is a human neurotropic polyomavirus whose replication in glial cells causes the fatal demyelinating disease progressive multifocal leukoencephalopathy (PML). In addition, JCV possesses oncogenic activity and expression of its transforming protein, large T-antigen (T-Ag), in several ex...

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Detalles Bibliográficos
Autores principales: Sariyer, Ilker Kudret, Merabova, Nana, Patel, Prem Kumer, Knezevic, Tijana, Rosati, Alessandra, Turco, Maria C., Khalili, Kamel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440322/
https://www.ncbi.nlm.nih.gov/pubmed/22984599
http://dx.doi.org/10.1371/journal.pone.0045000