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Dynamic Link between Histone H3 Acetylation and an Increase in the Functional Characteristics of Human ESC/iPSC-Derived Cardiomyocytes

Cardiomyocytes (CMs) derived from human embryonic stem cells (hESCs) or human induced pluripotent stem cells (hiPSCs) are functionally heterogeneous, display insufficient biological efficacy and generally possess the electrophysiological properties seen in fetal CMs. However, a homogenous population...

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Detalles Bibliográficos
Autores principales: Otsuji, Tomomi G., Kurose, Yuko, Suemori, Hirofumi, Tada, Masako, Nakatsuji, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440326/
https://www.ncbi.nlm.nih.gov/pubmed/22984602
http://dx.doi.org/10.1371/journal.pone.0045010