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Runx1 and Runx3 Are Involved in the Generation and Function of Highly Suppressive IL-17-Producing T Regulatory Cells

CD4(+)Foxp3(+) T regulatory cells (Tregs) display phenotypic and functional plasticity that is regulated by cytokines and other immune cells. Previously, we determined that during co-culture with CD4(+)CD25(−) T cells and antigen presenting cells, Tregs produced IL-17. Here, we investigated the mech...

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Detalles Bibliográficos
Autores principales: Li, Lequn, Patsoukis, Nikolaos, Petkova, Victoria, Boussiotis, Vassiliki A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440330/
https://www.ncbi.nlm.nih.gov/pubmed/22984619
http://dx.doi.org/10.1371/journal.pone.0045115