Localization Microscopy (SPDM) Reveals Clustered Formations of P-Glycoprotein in a Human Blood-Brain Barrier Model

P-glycoprotein (Pgp; also known as MDR1, ABCB1) is the most important and best studied efflux transporter at the blood-brain barrier (BBB); however, the organization of Pgp is unknown. The aim of this study was to employ the recently developed super-resolution fluorescence microscopy method spectral...

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Detalles Bibliográficos
Autores principales: Huber, Olga, Brunner, Alexander, Maier, Patrick, Kaufmann, Rainer, Couraud, Pierre-Olivier, Cremer, Christoph, Fricker, Gert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440331/
https://www.ncbi.nlm.nih.gov/pubmed/22984556
http://dx.doi.org/10.1371/journal.pone.0044776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440331/
https://www.ncbi.nlm.nih.gov/pubmed/22984556
http://dx.doi.org/10.1371/journal.pone.0044776

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