Heparin-Binding EGF-Like Growth Factor Induces Heart Interstitial Fibrosis via an Akt/mTor/p70s6k Pathway

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is essential for maintaining normal function of the adult heart and is known to play an important role in myocardial remodeling. In the present study, we observed that heart-specific HB-EGF transgenic (TG) mice had systolic dysfunct...

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Detalles Bibliográficos
Autores principales: Lian, Hong, Ma, Yuanwu, Feng, Juan, Dong, Wei, Yang, Qing, Lu, Dan, Zhang, Lianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440333/
https://www.ncbi.nlm.nih.gov/pubmed/22984591
http://dx.doi.org/10.1371/journal.pone.0044946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440333/
https://www.ncbi.nlm.nih.gov/pubmed/22984591
http://dx.doi.org/10.1371/journal.pone.0044946

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