β3 Integrin in Cardiac Fibroblast Is Critical for Extracellular Matrix Accumulation during Pressure Overload Hypertrophy in Mouse

The adhesion receptor β3 integrin regulates diverse cellular functions in various tissues. As β3 integrin has been implicated in extracellular matrix (ECM) remodeling, we sought to explore the role of β3 integrin in cardiac fibrosis by using wild type (WT) and β3 integrin null (β3−/−) mice for in vi...

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Detalles Bibliográficos
Autores principales: Balasubramanian, Sundaravadivel, Quinones, Lakeya, Kasiganesan, Harinath, Zhang, Yuhua, Pleasant, Dorea L., Sundararaj, Kamala P., Zile, Michael R., Bradshaw, Amy D., Kuppuswamy, Dhandapani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440340/
https://www.ncbi.nlm.nih.gov/pubmed/22984613
http://dx.doi.org/10.1371/journal.pone.0045076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440340/
https://www.ncbi.nlm.nih.gov/pubmed/22984613
http://dx.doi.org/10.1371/journal.pone.0045076

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