A p53-Pax2 Pathway in Kidney Development: Implications for Nephrogenesis

Congenital reduction in nephron number (renal hypoplasia) is a predisposing factor for chronic kidney disease and hypertension. Despite identification of specific genes and pathways in nephrogenesis, determinants of final nephron endowment are poorly understood. Here, we report that mice with germ-l...

Descripción completa

Detalles Bibliográficos
Autores principales: Saifudeen, Zubaida, Liu, Jiao, Dipp, Susana, Yao, Xiao, Li, Yuwen, McLaughlin, Nathaniel, Aboudehen, Karam, El-Dahr, Samir S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440354/
https://www.ncbi.nlm.nih.gov/pubmed/22984579
http://dx.doi.org/10.1371/journal.pone.0044869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440354/
https://www.ncbi.nlm.nih.gov/pubmed/22984579
http://dx.doi.org/10.1371/journal.pone.0044869

Ejemplares similares